University Of Southern California Study Explains Major Cause Of Drug-Resistance In Chronic Myeloid Leukemia

Researchers at the Keck School of Medicine of the University of Southern California (USC) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) have discovered high concentrations of a specific mutator protein in cells that develop resistance to drug treatment in chronic myeloid leukemia (CML). The finding helps explain why CML cells become drug-resistant and may lead to the development of therapies that improve survival in CML patients.